Arzneimittel mischen als HP

[Silke Uhlendahl]

-Vitamin C 1000 +  NaCL+ Vitamin B12

Diese Mischung sollte NIEMAND herstellen und das aus gutem Grund. Ascorbinsäure zerstört das Cobalamin (McEvoy 2007).

1. Herbert V, Jacob E. Destruction of Vitamin B12 by Ascorbic Acid. JAMA. 1974;230(2):241-242.
   
   
2. Frost DV et al L. Differential stability of various analogs of cobalamin to vitamin C. Science. 1952 Aug 1;116(3005):119-21.
   
   
3. Hastings H. Hutchins, Patricia J. Cravioto, Thomas J. Macek, A Comparison of the Stability of Cyanocobalamin and Its Analogs in Ascorbate Solution. Journal of the American Pharmaceutical Association (Scientific ed.), Volume 45, Issue 12, 1956, Pages 806-808, ISSN 0095-9553
   
   
4. Newmark HL, Scheiner MS, Marcus M, Prabhudesai M. Stability of vitamin B12 in the presence of ascorbic acid. Am J Clin Nutr. 1976 Jun;29(6):645-9.
   
   
5. Herbert V, Jacob E, Wong KT, Scott J, Pfeffer RD. Low serum vitamin B12 levels in patients receiving ascorbic acid in megadoses: studies concerning the effect of ascorbate on radioisotope vitamin B12 assay. Am J Clin Nutr. 1978 Feb;31(2):253-8.
   
   
6. Marcus M, Prabhudesai M, Wassef S. Stability of vitamin B12 in the presence of ascorbic acid in food and serum: restoration by cyanide of apparent loss. Am J Clin Nutr. 1980 Jan;33(1):137-43.
   
   
7. Newmark HL, Scheiner JM, Marcus M, Prabhudesai M. Ascorbic acid and vitamin B12. JAMA. 1979 Nov 23;242(21):2319-20.
   
   
8. Hogenkamp HP. The interaction between vitamin B12 and vitamin C. Am J Clin Nutr. 1980 Jan;33(1):1-3.
   
   
9. Ekvall S, Chen IW, Bozian R. The effect of supplemental ascorbic acid on serum vitamin B12 levels in myelomeningocele patients. Am J Clin Nutr. 1981 Jul;34(7):1356-61.
   
   
10. Watson WS, Vallance BD, Muir MM, Hume R. The effect of megadose ascorbic acid ingestion on the absorption and retention of vitamin B12 in man. Scott Med J. 1982 Jul;27(3):240-3.
    
    
11. Kondo, H., Binder, M. J., Kolhouse, J. F., Smythe, W. R., Podell, E. R., & Allen, R. H. (1982). Presence and formation of cobalamin analogues in multivitamin-mineral pills. Journal of Clinical Investigation, 70(4), 889–898.
    
    
12. Thenen SW. Megadose effects of vitamin C on vitamin B-12 status in the rat. J Nutr. 1989 Aug;119(8):1107-14. PubMed PMID: 2778537.
    
    
13. Simon JA, Hudes ES. Relation of Serum Ascorbic Acid to Serum Vitamin B12, Serum Ferritin, and Kidney Stones in US Adults. Arch Intern Med. 1999;159(6):619-624.
    
    
14. Ahmad I, Qadeer K, Zahid S, Sheraz MA, Ismail T, Hussain W, Ansari IA. Effect of ascorbic acid on the degradation of cyanocobalamin and hydroxocobalamin in aqueous solution: a kinetic study. AAPS PharmSciTech. 2014 Oct;15(5):1324-33.
    
    

 Hier sind weitere Studien zu finden 

Eine Zusammenfassung findet man hier:

https://www.vitaminb12.de/vitamin-b12-vitamin-c/